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- Details for Tiamulin Hydrogen Fumarate
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Tiamulin Hydrogen Fumarate 55297-96-6
Category : Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents
CAS NO : 55297-96-6 EC NO : 259-581-6 MF : C32H51NO8S MW : 609.8142 Specification : EP/USP/Feed Grade Packing : 25kg Drum net eadch Product description : TIAMULIN
COMMON NAME: Tiamulin Hydrogen Fumarate
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MOLECULAR FORMULAR: C28H47NO4S·C4H4O4
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MOLECULAR WEIGHT: 609.82
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SPECIFICATION
Items
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Technical Specifications
Specifications
Appearance
White crystal powder
Identification
IR-spectrum/HPLC retention times
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pH
From 3.1 to 4.1
Loss on drying
Not more than 0.5%
Heavy Metals (ppm)
Not more than 10
Fumarate assay
18.6-19.4%
Assay (HPLC)
98.0-102.0%
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INDICATION
Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E. coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin.
Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.
Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.
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CAUTION
Dont use together with polyether ionophores such as Monesin, Salinomycin etc.
Dont touch with eyes and skin.
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STORAGE
Keep in dry ,cool places; Seal the bag after use.
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PACKAGE
25 Kg/Drum
Uses : Antibiotic for Animal Use Synonyms : Tiamuline Hydrogen Fumarate;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;DENAGARD;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu;Tiamulin Fumarate;(4R,5S,6S,8R,9aS,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);(3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt); Molecular Structure : 
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Tiamulin Hydrogen Fumarate